Keratin-Positive Giant Cell-Rich Tumor in Early Infancy: Metastatic Presentation and Imatinib Response

This case expands the clinical spectrum of pediatric KPGCT and suggests that imatinib may be an effective treatment option in infants with advanced disease, even canonical HMGA2::NCOR2 fusion absent.

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Publication Details

Journal
Journal of Pediatric Hematology/Oncology
Published
2026-02-24
DOI
https://doi.org/10.1097/mph.0000000000003177
Primary Topic
Bone Tumor Diagnosis and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Keratin-Positive Giant Cell-Rich Tumor in Early Infancy: Metastatic Presentation and Imatinib Response

Can Berk Leblebici, Nihal Ekin Dağ, Sonay İncesoy Özdemir, Koray Ceyhan et al.
Journal of Pediatric Hematology/Oncology
Bone Tumor Diagnosis and Treatments
article

Keratin-Positive Giant Cell-Rich Tumor in Early Infancy: Metastatic Presentation and Imatinib Response

Can Berk Leblebici, Nihal Ekin Dağ, Sonay İncesoy Özdemir, Koray Ceyhan, Handan Dinçaslan, Nur Ayça Çelik, Nurdan Taçyildiz, Suat Fítöz, Nüket Yürür Kutlay, CEM Canakci, Seda Kaynak Şahap, Vafa Maharramova, Melda Berber Hamamci, Nubar Mustafayeva
article en

Abstract

This case expands the clinical spectrum of pediatric KPGCT and suggests that imatinib may be an effective treatment option in infants with advanced disease, even canonical HMGA2::NCOR2 fusion absent.

Journal of Pediatric Hematology/OncologyVol. 48(3)
Pediatric Oncology Group (CA), Ankara University (TR)
Good health and well-being
Openalex Percentile: Top 24%
Bone Tumor Diagnosis and Treatments
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