The superficial subplate as an in vivo imaging biomarker of normal cortical development in humans- a 3T MRI feasibility study

The superficial subplate is visible on T2-w in vivo fetal MRI at 3T. A deeper understanding of the in vivo appearance of the laminar organization of the human fetal brain, including the superficial subplate, is required to accurately interpret altered fetal brain development, thereby improving early diagnostic accuracy, reducing false-positive assessments, and supporting prenatal counselling in cases of suspected cortical malformations.

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Publication Details

Journal
American Journal of Neuroradiology
Published
2026-03-11
DOI
https://doi.org/10.3174/ajnr.a9290
Primary Topic
Fetal and Pediatric Neurological Disorders
Type
article
Field-Weighted Citation Impact
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article

The superficial subplate as an in vivo imaging biomarker of normal cortical development in humans- a 3T MRI feasibility study

Luca Pasquini, Miloš Judáš, Andrija Štajduhar, Dr Daniela Prayer et al.
American Journal of Neuroradiology
Fetal and Pediatric Neurological Disorders
article

The superficial subplate as an in vivo imaging biomarker of normal cortical development in humans- a 3T MRI feasibility study

Luca Pasquini, Miloš Judáš, Andrija Štajduhar, Dr Daniela Prayer, Ivana Pogledić, Mihaela Bobic-Rasonja, Jewgeni Bolotin, Natasa Jovanov-Milosevic, Kshitij Mankad, Christian Mitter, Gregor Kasprian, Marija Milković-Periša
article en

Abstract

The superficial subplate is visible on T2-w in vivo fetal MRI at 3T. A deeper understanding of the in vivo appearance of the laminar organization of the human fetal brain, including the superficial subplate, is required to accurately interpret altered fetal brain development, thereby improving early diagnostic accuracy, reducing false-positive assessments, and supporting prenatal counselling in cases of suspected cortical malformations.

American Journal of Neuroradiology
Medical University of Vienna (AT)
Good health and well-being
Openalex Percentile: Top 25%
Fetal and Pediatric Neurological Disorders
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