Burden of mental disorders in working-age populations (15–64 years) from 1990 to 2021 with projections to 2045: a global analysis of India, China and the United States

This study provides the most detailed, age-stratified evaluation of mental disorder burden among working-age populations to date. The findings highlight persistent gender and regional disparities and demonstrate the urgent need for scalable, culturally sensitive mental health interventions, workforce-based support systems, and the integration of mental health care into primary and occupational health frameworks.