Metabolomic analysis of arterial blood near intracranial occlusions reveals biochemical signatures of acute ischemic stroke
Arterial blood metabolomics reveals metabolic reprogramming associated with acute ischemic injury and compensatory responses. These findings support the potential use of metabolomic profiling for patient stratification and therapeutic decision-making, which requires validation in independent cohorts.
Authors
- Federico Sabuzi (ORCID: https://orcid.org/0000-0002-8284-755X)
- Martina Lombardi (ORCID: https://orcid.org/0000-0003-4453-6627)
- Alessio Trotta (ORCID: https://orcid.org/0009-0006-3589-7147)
- Armando Ugo Cavallo (ORCID: https://orcid.org/0000-0001-8390-7721)
- Vera Abenante (ORCID: https://orcid.org/0009-0001-6414-5722)
- Mariafrancesca Trulli
- Andrea Ingenito
- Nicole Palmieri
- Francesca Di Giuliano
- J. Troisi
- Renato Argiro’
- Marco Nezzo
- Daniele Morosetti
- Francesco Garaci
- Valerio Da Ros
Institutions
- University of Rome Tor Vergata (IT)
- Istituto Dermopatico dell'Immacolata (IT)
- Regione Puglia (IT)
- Policlinico Tor Vergata (IT)
Publication Details
- Journal
- Journal of Stroke and Cerebrovascular Diseases
- Published
- 2026-03-11
- DOI
- https://doi.org/10.1016/j.jstrokecerebrovasdis.2026.108608
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00