Contemporary and evolving perspectives on surgical therapies for essential tremor: deep brain stimulation and focused ultrasound

DBS may be preferred for younger patients, those needing long-term modulation, or bilateral therapy. FUS is an appealing option for older individuals or those with surgical contraindications. Directional and closed-loop DBS as well as connectomics-based targeting are likely to define the next generation of ET interventions, offering more personalized, durable, and safer tremor control.