Is CXCR4 Theranostics in Oncologic, Cardiovascular, and Inflammatory Diseases Really Happening?
C-X-C motif chemokine receptor 4 (CXCR4) is a transmembrane chemokine receptor involved in various biologic processes, including tumor growth, metastasis, and the homing and retention of hematopoietic stem cells or progenitors in hematopoietic sites ([1][1]). Under physiologic conditions, CXCR4 is
Authors
- Philipp E. Hartrampf (ORCID: https://orcid.org/0000-0001-5622-9849)
- Andreas K. Buck (ORCID: https://orcid.org/0000-0002-6447-0613)
- Rudolf Werner
- Takahiro Higuchi
- Margret Schottelius
Institutions
- Universitätsklinikum Würzburg (DE)
- Swiss Cancer Center Léman (CH)
- Comprehensive Cancer Center Erlangen (DE)
- Ludwig-Maximilians-Universität München (DE)
- University of Lausanne (CH)
Publication Details
- Journal
- Journal of Nuclear Medicine
- Published
- 2026-03-12
- DOI
- https://doi.org/10.2967/jnumed.125.271153
- Primary Topic
- Chemokine receptors and signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft