Active Components and Potential Mechanism of Redujing Oral Liquid forTreating EBV Infection: A UHPLC-MS and Network Pharmacology-Based Approach
This study systematically characterized the active components of RDJ and revealed its anti-EBV mechanisms through an integrated approach combining chemical profiling and network pharmacology. The identified components and pathways, particularly baicalein-mediated regulation of PIK3CA, offer a theoretical foundation for advancing RDJ in clinical and translational research for EBV-associated diseases.
Authors
- Hong Cui
- Weijing Kong (ORCID: https://orcid.org/0000-0002-4854-6219)
- XT Li
- Yanqing Yao
Institutions
- Beijing Friendship Hospital (CN)
- Beijing Ditan Hospital (CN)
Publication Details
- Journal
- Combinatorial Chemistry & High Throughput Screening
- Published
- 2026-03-11
- DOI
- https://doi.org/10.2174/0113862073389910250703111252
- Primary Topic
- Viral-associated cancers and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00