Language-related functional connectivity in post-stroke aphasia: preliminary findings from a graph-theoretical and interpretable machine learning study

Our findings suggest that the high-level group relies on a synergistic interaction between the ventral stream (toITG) and the dorsal stream (pSMG). The shift toward increased local specialization, particularly the compensatory recruitment of the right pSMG, highlights a critical neural modularity strategy for functional recovery. These results suggest the feasibility of integrating graph metrics with interpretable machine learning, offering preliminary insights that could support the development of objective tools for monitoring aphasia rehabilitation.

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Publication Details

Journal
International Journal of Neuroscience
Published
2026-03-13
DOI
https://doi.org/10.1080/00207454.2026.2644508
Primary Topic
Neurobiology of Language and Bilingualism
Type
article
Field-Weighted Citation Impact
0.00
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article

Language-related functional connectivity in post-stroke aphasia: preliminary findings from a graph-theoretical and interpretable machine learning study

Christof Karmonik, Abo Masahiro, Ngoc Thanh Hoang, Niluka Dilhani et al.
International Journal of Neuroscience
Neurobiology of Language and Bilingualism
article

Language-related functional connectivity in post-stroke aphasia: preliminary findings from a graph-theoretical and interpretable machine learning study

Christof Karmonik, Abo Masahiro, Ngoc Thanh Hoang, Niluka Dilhani, Thishuli Walpola, Atsushi Senoo
article en

Abstract

Our findings suggest that the high-level group relies on a synergistic interaction between the ventral stream (toITG) and the dorsal stream (pSMG). The shift toward increased local specialization, particularly the compensatory recruitment of the right pSMG, highlights a critical neural modularity strategy for functional recovery. These results suggest the feasibility of integrating graph metrics with interpretable machine learning, offering preliminary insights that could support the development of objective tools for monitoring aphasia rehabilitation.

International Journal of Neuroscience
Jikei University School of Medicine (JP), Houston Methodist (US), Cornell University (US), Hue University (VN), Methodist Hospital (US), Tokyo Metropolitan University (JP)
Openalex Percentile: Top 29%
Neurobiology of Language and Bilingualism
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