Optimizing VCTE and ELF Thresholds for Treatment‐Eligible F2–F3 Fibrosis in Japanese Patients With MASLD
Western guideline-recommended VCTE and ELF cutoffs showed high sensitivity in Japanese patients and can be used to exclude cirrhosis. Because the likelihood of cirrhosis increases with VCTE > 15 kPa or ELF > 10.5, treatment eligibility should be determined in conjunction with other clinical information, and confirmatory assessment should be considered when appropriate.
Authors
- Kazuhito Kawata (ORCID: https://orcid.org/0000-0002-4986-8578)
- Toshihide Shima (ORCID: https://orcid.org/0000-0002-4120-9121)
- Michihiro Iwaki (ORCID: https://orcid.org/0000-0002-7650-0699)
- Yoshio Sumida (ORCID: https://orcid.org/0000-0002-4342-1361)
- Tomohisa Takagi (ORCID: https://orcid.org/0000-0002-6119-4828)
- H. Toyoda
- Hideki Hayashi (ORCID: https://orcid.org/0000-0003-0632-907X)
- Yoshihiro Kamada
- H. Fujii (ORCID: https://orcid.org/0000-0001-5738-4680)
- Kazuo Notsumata (ORCID: https://orcid.org/0000-0002-1211-3227)
- Masanori Atsukawa (ORCID: https://orcid.org/0000-0003-3374-7111)
- Asahiro Morishita (ORCID: https://orcid.org/0000-0002-0760-3045)
- Tadashi Ikegami (ORCID: https://orcid.org/0000-0001-8913-5232)
- Yuichi Yoshida (ORCID: https://orcid.org/0000-0002-7025-7675)
- Shinichi Aishima
- Taeang Arai
- Yuya Seko
- E Miyoshi
- Kanji Yamaguchi
- Satoshi Oeda
- Miwa Kawanaka
- Kengo Tomita
- Masato Yoneda
- Hirokazu Takahashi
- Atsushi Nakajima
- Takeshi Okanoue
Institutions
- Kyushu University (JP)
- Okayama University of Science (JP)
- Okayama University (JP)
- Saga University (JP)
- Kagawa University (JP)
- Hamamatsu University School of Medicine (JP)
- Takamatsu University (JP)
- Osaka City University (JP)
- Kyoto Prefectural University of Medicine (JP)
- National Defense Medical College Hospital (JP)
- Municipal Tsuruga Hospital (JP)
- Okayama University Hospital (JP)
- Gifu Municipal Hospital (JP)
- Ogaki Municipal Hospital (JP)
- Suita Municipal Hospital (JP)
- Saiseikai Suita Hospital (JP)
- Tokyo Medical University Ibaraki Medical Center (JP)
- International University Of Health And Welfare Atami Hospital (JP)
- Osaka Metropolitan University (JP)
- National Defense Medical College (JP)
- Tokyo Metropolitan University (JP)
- International University of Health and Welfare (JP)
- Nippon Medical School (JP)
- Yokohama City University (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Hepatology Research
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1111/hepr.70155
- Primary Topic
- Cystic Fibrosis Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 0.00