Photobiomodulation pre-treatment enhances ALA-induced PpIX accumulation and photodynamic therapy response in oral squamous cell carcinoma cells in cell culture
PBM enhances ALA-induced PpIX accumulation, and subsequent PDT response in OSCC cells. This enhancement effect can be achieved using the same light source as for PpIX photoactivation suggesting potential as a clinically practical pre-treatment to enhance efficacy of ALA-PDT.
Authors
- Ana Paula Ferro (ORCID: https://orcid.org/0009-0009-4602-866X)
- Yi Ran Liu
- Elaine Caldeira de Oliveira Guirro (ORCID: https://orcid.org/0000-0002-1045-8053)
- Sally Kyei Mensah
- Jonathan P. Celli
Institutions
- Universidade de São Paulo (BR)
- University of Massachusetts Boston (US)
Publication Details
- Journal
- Photodiagnosis and Photodynamic Therapy
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1016/j.pdpdt.2026.105433
- Primary Topic
- Laser Applications in Dentistry and Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00