Serum Uric Acid Levels As A Prognostic Indicator in Acute Ischaemic Stroke

Abstract Introduction: Stroke remains a major public health concern worldwide, contributing significantly to morbidity and mortality. Among the different types of strokes, ischemic stroke accounts for the majority of cases, occurring due to the occlusion of cerebral arteries and subsequent ischemic injury. Stroke is the second leading cause of death globally, significantly affecting individuals, families and healthcare systems. Objectives Primary Objective: To study the serum uric acid levels in acute ischemic stroke and assess its prognostic significance. Secondary Objective: To study the association between serum uric acid and various risk factors for stroke. Material and Method: Study Design: Prospective observational study Study Period: 12 months from IEC approval (August 2023 to August 2024) Study Setting: Department of General Medicine, Govt. Medical College, Ernakulam Sample Population: Patients admitted to General medicine wards of Government medical college, Ernakulam with diagnosis of acute ischemic stroke satisfying the inclusion criteria and exclusion criteria. Sampling Method: Consecutive sampling Study Tool: Semi Structured peer reviewed proforma. Result: The study involved 120 participants and the findings revealed that the mean age of stroke patients was 63.25 years, with a male predominance (56.7%). Discussion: Among the study population, hypertension (65%) and dyslipidemia (58.3%) were the most common comorbidities, followed by diabetes (48.3%) and smoking (40.8%). Keywords: Antioxidant, Cyclosporine, Dyslipidemia, Ischemic Stroke, Serum Uric Acid.