Efficacy and safety of intravenous versus oral corticosteroid therapy in Graves’ ophthalmopathy: a systematic review and meta-analysis of randomized controlled trials

IV steroids were associated with more favourable outcomes and better tolerability than oral steroids in moderate-to-severe GO. Further comprehensive trials are needed to confirm long-term safety and optimize treatment protocols.

Authors

Institutions

Publication Details

Journal
Orbit
Published
2026-03-12
DOI
https://doi.org/10.1080/01676830.2026.2623007
Primary Topic
Ophthalmology and Eye Disorders
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Efficacy and safety of intravenous versus oral corticosteroid therapy in Graves’ ophthalmopathy: a systematic review and meta-analysis of randomized controlled trials

S Hamoud Alotaibi, Hanin Ayed M. Alghamdi, Ibtisam Ahmed Algouf, Mamoun Mazin Alrefaai et al.
Orbit
Ophthalmology and Eye Disorders
article

Efficacy and safety of intravenous versus oral corticosteroid therapy in Graves’ ophthalmopathy: a systematic review and meta-analysis of randomized controlled trials

S Hamoud Alotaibi, Hanin Ayed M. Alghamdi, Ibtisam Ahmed Algouf, Mamoun Mazin Alrefaai, Eyad Mohammad Hijazi, Raed Behbahani, Arwa Hussain Alhareth, Fahad Faisal Aldhaban, Marwa Ahmed Akram, Layan Abdulrahman Alraddadi, Mazin Elfatih Abdelgadir, Razan Abdulrahim Almalki, Noura Faihan Almutairi
article en

Abstract

IV steroids were associated with more favourable outcomes and better tolerability than oral steroids in moderate-to-severe GO. Further comprehensive trials are needed to confirm long-term safety and optimize treatment protocols.

Orbit
Alfaisal University (SA), Qassim University (SA), Taif University (SA), Mubarak Al Kabeer Hospital (KW), University of Jeddah (SA), Centre Hospitalier Ibn Sina (MA), Joint Research Centre (DE), Ibn Sina Hospital (KW), Almaarefa University, King Faisal University (SA), Najran University (SA), Atatürk University (TR), University of Tabuk (SA)
Good health and well-being
Openalex Percentile: Top 27%
Ophthalmology and Eye Disorders
DOISourceOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Efficacy and safety of intravenous versus oral corticosteroid therapy in Graves’ ophthalmopathy: a systematic review and meta-analysis of randomized controlled trials — S Hamoud Alotaibi, Hanin Ayed M. Alghamdi, et al. · Orbit (2026) | TGRS Research Map | TGRS