Update on total intravenous anesthesia in children
Pediatric TIVA is moving toward greater precision, safety, and sustainability. Moderate effect-site targets, opioid titration, and early down-titration remain central, particularly in neonates. Propofol infusion syndrome is exceedingly rare, and organ-protective effects of TIVA are reported in major surgery. Despite clinical and environmental advantages, adoption varies globally due to limited training, variable pump availability, and regulatory barriers. Expanding structured education and pediatric-specific TCI tools is essential for broader implementation.
Authors
- Ricardo Vieira Carlos (ORCID: https://orcid.org/0000-0002-5787-8979)
- Vinícius Caldeira Quintão (ORCID: https://orcid.org/0000-0001-6459-7983)
- Britta S. von Ungern-Sternberg
Institutions
- The Kids Research Institute Australia (AU)
- The University of Western Australia (AU)
- Universidade de São Paulo (BR)
- Princess Margaret Hospital for Children (AU)
- Association of Perioperative Registered Nurses (US)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
- Fundação Faculdade de Medicina (BR)
- Instituto do Coração (PT)
Publication Details
- Journal
- Current Opinion in Anaesthesiology
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1097/aco.0000000000001635
- Primary Topic
- Anesthesia and Neurotoxicity Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00