Efficacy and safety of brexpiprazole in early-episode schizophrenia: post hoc analysis of Phase 3 clinical trials in adults and adolescents

This analysis expands the evidence base for brexpiprazole in schizophrenia by demonstrating efficacy in patients who are early in their disease course. The safety profile of brexpiprazole was consistent with previous clinical trials.

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Publication Details

Journal
Psychiatry Research
Published
2026-03-12
DOI
https://doi.org/10.1016/j.psychres.2026.117091
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy and safety of brexpiprazole in early-episode schizophrenia: post hoc analysis of Phase 3 clinical trials in adults and adolescents

Anton Palma, Brian K. Pflug, Christoph U. Correll, Zhen Zhang et al.
Psychiatry Research
Schizophrenia research and treatment
article

Efficacy and safety of brexpiprazole in early-episode schizophrenia: post hoc analysis of Phase 3 clinical trials in adults and adolescents

Anton Palma, Brian K. Pflug, Christoph U. Correll, Zhen Zhang, Tim Pham, Murat Yildirim
article en

Abstract

This analysis expands the evidence base for brexpiprazole in schizophrenia by demonstrating efficacy in patients who are early in their disease course. The safety profile of brexpiprazole was consistent with previous clinical trials.

Psychiatry ResearchVol. 360
Lundbeck (Denmark) (DK), Otsuka (United States) (US), German Centre for Cardiovascular Research (DE), Otsuka (United Kingdom) (GB)
Good health and well-being
Openalex Percentile: Top 34%
Schizophrenia research and treatment
DOIOpen Access PDFOpenAlex
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