Effects of doxycycline post-exposure prophylaxis on bacterial sexually transmitted infections and antiretroviral therapy adherence among adolescents and young adults living with HIV

Doxy PEP was not associated with significant reductions in STI positivity in this adolescent and young adult cohort. Although non-significant, directional patterns were observed in syphilis outcomes; these outcomes should be interpreted with caution, given the small sample size. ART adherence remained unaffected, supporting the feasibility of incorporating Doxy PEP into youth HIV programs. Larger studies are needed to clarify Doxy PEP's effectiveness among adolescents and young adults.