Occupational exposure to chlorinated solvents and lung cancer: results of the SYNERGY case–control study

This pooled analysis provides limited evidence of an association between occupational exposure to chlorinated solvents and lung cancer, though exposure-response trends were noted among exposed individuals.

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Publication Details

Journal
Occupational and Environmental Medicine
Published
2026-03-12
DOI
https://doi.org/10.1136/oemed-2025-110129
Primary Topic
Carcinogens and Genotoxicity Assessment
Type
article
Field-Weighted Citation Impact
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article

Occupational exposure to chlorinated solvents and lung cancer: results of the SYNERGY case–control study

Beata Świątkowska, Christine Barul, L. Portengen, M. T. Landi et al.
Occupational and Environmental Medicine
Carcinogens and Genotoxicity Assessment
article

Occupational exposure to chlorinated solvents and lung cancer: results of the SYNERGY case–control study

Beata Świątkowska, Christine Barul, L. Portengen, M. T. Landi, Lorenzo Richiardi, Francesco Forastiere, H. Kromhout, Benjamin Kendzia, J Siemiatycki, John K. Field, Lenka Foretová, Stefan Karrasch, Wendy Bijoux, Miriam Schejbalová, Loredana Radoï, F. Merletti, Tamás Pándics, K‐H Jöckel, Guillermo Fernandez-Tardon, Dana Mates, David Zaridze, Thomas Behrens, Thomas Brüning, Per Gustavsson, Roel Vermeulen, Calvin B Ge, Wenxin Wan, Ann Olsson, Joachim Schüz, Vladimir Janout, Eleonora Fabianova, Enrica Migliore, Heinz-Erich Wichmann, Neil E Caporaso, Hermann Pohlabeln, Paul A Demers, Kurt Straif, Jolanta Lissowska, John McLaughlin, Wolfgang Ahrens, Susan Peters, Dario Consonni
article en

Abstract

This pooled analysis provides limited evidence of an association between occupational exposure to chlorinated solvents and lung cancer, though exposure-response trends were noted among exposed individuals.

Occupational and Environmental Medicine
Semmelweis University (HU), Boston College (US), University of Liverpool (GB), Netherlands Organisation for Applied Scientific Research (NL), Inserm (FR), Universidad de Oviedo (ES), Zimmer Biomet (Netherlands) (NL), University of Toronto (CA), Utrecht University (NL), Nofer Institute of Occupational Medicine (PL), Charles University (CZ), Roy Castle Lung Cancer Foundation (GB), Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT), Karolinska Institutet (SE), Helmholtz Zentrum München (DE), Institut für Medizinische Informatik, Biometrie und Epidemiologie (DE), Ospedale Maggiore (IT), Russian Cancer Research Center NN Blokhin (RU), Institut für Medizinische Biometrie, Informatik und Epidemiologie (DE), National Public Health and Medical Officer Service (HU), Centre de recherche en Epidémiologie et Santé des Populations (FR), Public Health Authority of the Slovak Republic (SK), Institut de Recherche en Santé, Environnement et Travail (FR), Occupational Cancer Research Centre (CA), Leibniz Institute for Prevention Research and Epidemiology - BIPS (DE), Masaryk Memorial Cancer Institute (CZ), National Institute of Oncology (HU), Institute for Prevention and Occupational Medicine (DE), München Klinik (DE), Public Health Ontario (CA), National Cancer Institute (US), Barcelona Institute for Global Health (ES), The Maria Sklodowska-Curie National Research Institute of Oncology (PL), National Center for Epidemiology (HU), Azienda Sanitaria Locale Roma 3 (IT), Catholic University in Ruzomberok (SK), Centre international de recherche sur le cancer (FR), Division of Cancer Epidemiology and Genetics, University of Turin (IT), Palacký University Olomouc (CZ), Université de Montréal (CA), Ludwig-Maximilians-Universität München (DE)
Good health and well-being
Openalex Percentile: Top 25%
Carcinogens and Genotoxicity Assessment
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