The albumin–bilirubin score can reflect disease severity in alcohol-associated hepatitis and cirrhosis

Aims: The albumin-bilirubin (ALBI) score has been evaluated in various liver diseases, however its clinical relevance in alcoholassociated liver disease (ALD) remains unclear. This study aimed to evaluate whether the ALBI score reflects disease severity in patients with alcohol-associated hepatitis (AH) and alcohol-associated cirrhosis (AC).Methods: In this retrospective case control study, 51 AH patients, 39 AC patients, and 48 healthy controls (HCs) were included. The ALBI score was calculated for all participants. The Child-Pugh classification (CPC A-C) was recorded for AC, while Maddrey’s Discriminant Function (MDF) for AH. The Model for End-Stage Liver Disease Sodium (MELD-Na) score was calculated for both patient groups, and the Fibrosis-4 (FIB-4) index was calculated in all participants. Results: Mean ALBI scores were highest in the AH patients and the lowest in the HCs (p