Efficacy and safety of secondary induction radiotherapy in locally advanced resectable esophageal squamous cell carcinoma with poor responses to neoadjuvant immunochemotherapy: a retrospective study
In patients with resectable ESCC and a poor response to nICT, secondary induction radiotherapy was associated with encouraging surgical and pathological outcomes and an acceptable safety profile. Prospective studies are warranted to confirm these findings.
Authors
- P F Zhang
- Xiaofeng Duan (ORCID: https://orcid.org/0009-0004-8076-3055)
- ZQ Tian
- W Ding
- X. S. Jiang (ORCID: https://orcid.org/0000-0002-2362-2756)
- L. Dai (ORCID: https://orcid.org/0000-0002-4070-4729)
- H. Lv
- Songping Xie
- Ke-Neng Chen
Institutions
- Hebei Medical University (CN)
- Peking University (CN)
- Tianjin Medical University Cancer Institute and Hospital (CN)
- Wuhan University (CN)
- Fourth Hospital of Hebei Medical University (CN)
- Peking University First Hospital (CN)
- Renmin Hospital of Wuhan University (CN)
- Ministry of Education (ET)
- Hebei University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-03-11
- DOI
- https://doi.org/10.3389/fimmu.2026.1656631
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Hebei Province