Development and validation of an immune-based nomogram model for predicting severe adenovirus pneumonia in hospitalized children
This study identified and validated seven independent factors significantly associated with SAP in children. A nomogram incorporating these factors was developed and it demonstrated favourable discriminative performance and good calibration. The model exhibited high sensitivity and maintained high predictive accuracy across both datasets, indicating its potential clinical utility for individualized risk stratification.
Authors
- Xiaolin Ma (ORCID: https://orcid.org/0000-0001-7538-772X)
- Wenquan niu
- Yuting Wu
- Ling Cao
Institutions
- Capital Institute of Pediatrics (CN)
- Capital Health (US)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2026-03-11
- DOI
- https://doi.org/10.3389/fped.2026.1742222
- Primary Topic
- Virus-based gene therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Beijing Municipal Administration of Hospitals