Association between glucagon-like peptide-1 receptor agonists and femur fracture risk in type 2 diabetes: A large-scale target trial emulation
GLP-1 RA use was associated with a modest reduction in femur fracture risk. However, given the observational design, possible residual confounding, and multiple testing, these findings are exploratory and require prospective confirmation before clinical application.
Authors
- Jie-Fan Chang
- Mengting Chen (ORCID: https://orcid.org/0000-0001-9379-6818)
- Chiou-Shann Fuh
- Yao-Jen Chang
- Ming-Hsien Tsai
Institutions
- National Taiwan University (TW)
- National Taiwan University Hospital (TW)
- Memorial Hospital (US)
Publication Details
- Journal
- Bone
- Published
- 2026-03-11
- DOI
- https://doi.org/10.1016/j.bone.2026.117851
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00