Case Report: Amplified psychoanalysis? Psychoanalysis, OCD and MDMA in a clinical case study

This article investigates the novel therapeutic approach of "amplified psychoanalysis" through a detailed examination of the Ygg case, which offers a descriptive single-case illustration of the integration of MDMA-assisted therapy with traditional psychoanalytic treatment for obsessive-compulsive disorder (OCD). The study explores how subjective experience induced by MDMA can interact with an ongoing analysis, potentially enhancing psychoanalytic processes by facilitating access to unconscious material and helping to move beyond therapeutic impasses. The work is presented as a psychoanalytic single-case clinical narrative, acknowledging the value of such cases for generating nuanced insights into psychological phenomena rather than for demonstrating efficacy. In this case, the integration of MDMA experiences within an established psychoanalytic framework appeared to create specific therapeutic opportunities: the altered states of consciousness were experienced by the patient as allowing more direct access to, and processing of, previously avoided memories and affects. This combination may be particularly promising for OCD, where traditional approaches often face limitations; however, its efficacy requires systematic investigation beyond this psychoanalytic single-case clinical narrative. The clinical process analysis highlights several putative processes of change, including enhanced emotional processing, a strengthened therapeutic alliance, and improved access to traumatic memories. The study aims to contribute to both psychedelic therapy and psychoanalytic practice by offering a novel therapeutic perspective on the treatment of OCD. It suggests that "amplified psychoanalysis" may represent a promising direction for future research with larger samples and formal outcome measures.

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Publication Details

Journal
Frontiers in Psychology
Published
2026-03-11
DOI
https://doi.org/10.3389/fpsyg.2026.1617428
Primary Topic
Psychedelics and Drug Studies
Type
article
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article

Case Report: Amplified psychoanalysis? Psychoanalysis, OCD and MDMA in a clinical case study

Filippo Dellanoce
Frontiers in Psychology
Psychedelics and Drug Studies
article

Case Report: Amplified psychoanalysis? Psychoanalysis, OCD and MDMA in a clinical case study

Filippo Dellanoce
article en

Abstract

This article investigates the novel therapeutic approach of "amplified psychoanalysis" through a detailed examination of the Ygg case, which offers a descriptive single-case illustration of the integration of MDMA-assisted therapy with traditional psychoanalytic treatment for obsessive-compulsive disorder (OCD). The study explores how subjective experience induced by MDMA can interact with an ongoing analysis, potentially enhancing psychoanalytic processes by facilitating access to unconscious material and helping to move beyond therapeutic impasses. The work is presented as a psychoanalytic single-case clinical narrative, acknowledging the value of such cases for generating nuanced insights into psychological phenomena rather than for demonstrating efficacy. In this case, the integration of MDMA experiences within an established psychoanalytic framework appeared to create specific therapeutic opportunities: the altered states of consciousness were experienced by the patient as allowing more direct access to, and processing of, previously avoided memories and affects. This combination may be particularly promising for OCD, where traditional approaches often face limitations; however, its efficacy requires systematic investigation beyond this psychoanalytic single-case clinical narrative. The clinical process analysis highlights several putative processes of change, including enhanced emotional processing, a strengthened therapeutic alliance, and improved access to traumatic memories. The study aims to contribute to both psychedelic therapy and psychoanalytic practice by offering a novel therapeutic perspective on the treatment of OCD. It suggests that "amplified psychoanalysis" may represent a promising direction for future research with larger samples and formal outcome measures.

Frontiers in PsychologyVol. 17
European Society of Cardiology (FR)
Openalex Percentile: Top 30%
Psychedelics and Drug Studies
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