Defining success in functional cure for chronic hepatitis B: a nationwide survey of physician benchmarks to guide clinical practice and trial design

Our findings translate the collective expertise of Chinese physicians into actionable benchmarks for HBV functional cure. The consensus on a minimal 30% cure rate and a preference for combination therapy provide crucial guidance for clinical trial design and the development of novel antiviral strategies.

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Publication Details

Journal
Frontiers in Public Health
Published
2026-03-11
DOI
https://doi.org/10.3389/fpubh.2026.1707447
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Defining success in functional cure for chronic hepatitis B: a nationwide survey of physician benchmarks to guide clinical practice and trial design

Yisi Liu, Sujun Zheng, Lina Ma, X Y Chen et al.
Frontiers in Public Health
Hepatitis B Virus Studies
article

Defining success in functional cure for chronic hepatitis B: a nationwide survey of physician benchmarks to guide clinical practice and trial design

Yisi Liu, Sujun Zheng, Lina Ma, X Y Chen, S Ren, Xiao Lin, Junefeng Lu
article en

Abstract

Our findings translate the collective expertise of Chinese physicians into actionable benchmarks for HBV functional cure. The consensus on a minimal 30% cure rate and a preference for combination therapy provide crucial guidance for clinical trial design and the development of novel antiviral strategies.

Frontiers in Public HealthVol. 14
Beijing YouAn Hospital (CN)
Beijing Municipal Health Commission, National Key Research and Development Program of China
Good health and well-being
Openalex Percentile: Top 28%
Hepatitis B Virus Studies
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