Interplay between colorectal cancer-related lifestyles and the gut microbiome: an exploratory analysis of metagenomic data
Participants with higher- and lower-risk lifestyles showed clear differences in their gut microbiome diversity and composition, higher-risk lifestyles being associated with potentially adverse microbial traits. These findings contribute to identifying microbial features that may characterize early stages of CRC development in individuals with high-risk lifestyles.
Authors
- Anne‐Maria Pajari (ORCID: https://orcid.org/0000-0002-6248-4560)
- Niina E. Kaartinen (ORCID: https://orcid.org/0000-0002-6812-2237)
- Mirkka Maukonen (ORCID: https://orcid.org/0000-0002-2179-6904)
- Guillaume Méric (ORCID: https://orcid.org/0000-0001-6288-9958)
- Rilla Tammi (ORCID: https://orcid.org/0000-0002-5507-2314)
- Aki S. Havulinna
- Satu Männistö
- Rob Knight
- Veikko Salomaa
- Teemu Niiranen
- Demetrius Albanes
- Kari Koponen
- Seppo Koskinen
- Pekka Jousilahti
- Johan G. Eriksson
Institutions
- National Institutes of Health (US)
- University of Helsinki (FI)
- Baker Heart and Diabetes Institute (AU)
- University of Turku (FI)
- The University of Melbourne (AU)
- University of Eastern Finland (FI)
- La Trobe University (AU)
- Helsinki University Hospital (FI)
- Turku University Hospital (FI)
- University of California San Diego (US)
- Finnish Institute for Health and Welfare (FI)
- Institute for Molecular Medicine Finland (FI)
- National Cancer Institute (US)
- Folkhälsans Forskningscentrum (FI)
- University of Bath (GB)
Publication Details
- Journal
- Cancer Causes & Control
- Published
- 2026-03-11
- DOI
- https://doi.org/10.1007/s10552-026-02144-1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Yrjö Jahnssonin Säätiö
- Juho Vainion Säätiö
- Strategic Research Council