Association between clinical and pathological factors and risk of radioiodine refractory in patients with differentiated thyroid carcinoma
The obtained data highlight the interplay between clinical and molecular factors in the development of radioiodine resistance in differentiated thyroid cancer (DTC). The co-occurrence of BRAF and TERT mutations has potential prognostic significance. These findings suggest that integrating clinical and molecular data enables more accurate risk stratification for radioiodine resistance and helps define the direction of future research.
Authors
- Altay Dyussupov (ORCID: https://orcid.org/0000-0003-0875-1020)
- Saltanat O. Bolsynbekova (ORCID: https://orcid.org/0009-0002-2462-1883)
- Andrey U. OREKHOV
- Maksim Pivin
- Aidana M. Rakhmankulova (ORCID: https://orcid.org/0009-0001-3119-0738)
- K. K. Kudaiberdinov
- Lyudmila M. Pivina
- Dana M. Seitkhanova
- Laura Pak
- Zhandos Burkitbayev
- Masahiro Nakashima
- Diana Pak
Institutions
- World Vision (US)
- Semey Medical University (KZ)
- Global Health Research Center of Central Asia (KZ)
- Nagasaki University Hospital (JP)
- Nagasaki University (JP)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2026-03-11
- DOI
- https://doi.org/10.3389/fendo.2026.1709736
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00