Sweep Gas Nitric Oxide During Extracorporeal Membrane Oxygenation in Neonates and Children (NECTAR Trial): A Single-Center, Pilot Randomized Controlled Trial
This single-center pilot RCT of sNO vs. standard sweep flow in the ECMO circuit demonstrated that such a trial is safe and feasible. However, given no effect of sNO on clinical outcomes was detected further exploration of dose and route of administration of NO should be undertaken before larger, definitive trials are conducted.
Authors
- Prem Venugopal (ORCID: https://orcid.org/0000-0002-0416-7823)
- Adrian Mattke
- Nelson Alphonso (ORCID: https://orcid.org/0000-0002-3735-8298)
- KRISTEN S. GIBBONS (ORCID: https://orcid.org/0000-0002-5679-0932)
- Antje Blumenthal (ORCID: https://orcid.org/0000-0003-3673-7015)
- Renate Le Marsney (ORCID: https://orcid.org/0000-0001-9271-8594)
- Kerry Johnson (ORCID: https://orcid.org/0000-0001-6022-1065)
- Christopher J. O’Brien
- Luregn J. Schlapbach
- Debbie A. Long
Institutions
- Children's Medical Research Institute (AU)
- Queensland University of Technology (AU)
- The University of Queensland (AU)
- Children’s Health Queensland Hospital and Health Service (AU)
- University Children's Hospital Zurich (CH)
- Children's Health Queensland Hospital and Health Service (AU)
Publication Details
- Journal
- Pediatric Critical Care Medicine
- Published
- 2026-03-11
- DOI
- https://doi.org/10.1097/pcc.0000000000003926
- Primary Topic
- Mechanical Circulatory Support Devices
- Type
- article
- Field-Weighted Citation Impact
- 0.00