CYFRA 21-1 in lymph node fine-needle aspiration washouts: added value in differentiated thyroid cancer
FNA-CYFRA 21-1 provides excellent diagnostic accuracy for metastatic cervical lymph nodes in DTC and performs at least comparably to established approaches. Its integration into a multimodal strategy may enhance diagnostic confidence, particularly in cytologically indeterminate or Tg-challenging scenarios.
Authors
- Lilla Bonanno (ORCID: https://orcid.org/0000-0002-0282-405X)
- Petra Petranović Ovčariček (ORCID: https://orcid.org/0000-0003-1946-2128)
- Martin William Huellner (ORCID: https://orcid.org/0000-0002-4849-3292)
- R. M. Ruggeri
- Alfredo Campenni
- Luca Giovanella
Institutions
- University of Messina (IT)
- University Hospital Centre Zagreb (HR)
- University Hospital of Zurich (CH)
- Sisters of Charity Hospital (HR)
- Clinica Luganese Moncucco (CH)
- Centro Neurolesi Bonino Pulejo (IT)
Publication Details
- Journal
- Clinical Chemistry and Laboratory Medicine (CCLM)
- Published
- 2026-03-11
- DOI
- https://doi.org/10.1515/cclm-2026-0251
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00