Clinical and functional characteristics of the KLF11 (p.R29Q) variant associated with MODY7
We studied a <i>KLF11</i> R29Q single-gene mutation associated with MODY7. The study confirmed that this variant has impaired insulin promoter regulatory activity and inhibits insulin expression and secretion.
Authors
- Guijun Qin (ORCID: https://orcid.org/0000-0002-2503-7534)
- M. Zhang (ORCID: https://orcid.org/0000-0001-8659-5727)
- D. Song (ORCID: https://orcid.org/0000-0002-6334-181X)
- Yanyan Jiang
- Yanxia Liu
- Ying Xin
- Yidan Qiao
- Yi Song
Institutions
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2026-03-11
- DOI
- https://doi.org/10.3389/fendo.2026.1781016
- Primary Topic
- Kruppel-like factors research
- Type
- article
- Field-Weighted Citation Impact
- 0.00