Serum ferritin change rate combined with a multidimensional inflammation model for predicting efficacy and survival in extensive-stage small-cell lung cancer patients undergoing immunotherapy: a single-center, retrospective cohort study

Our study suggests that the serum ferritin change rate combined with the NLR and LDH inflammation model can serve as a biomarker for predicting the efficacy and survival outcomes of immunotherapy in ES-SCLC.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-03-11
DOI
https://doi.org/10.3389/fimmu.2026.1755851
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00

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article

Serum ferritin change rate combined with a multidimensional inflammation model for predicting efficacy and survival in extensive-stage small-cell lung cancer patients undergoing immunotherapy: a single-center, retrospective cohort study

Xin Liu, M Z Li, Yalan Liu, Yudong Su et al.
Frontiers in Immunology
Ferroptosis and cancer prognosis
article

Serum ferritin change rate combined with a multidimensional inflammation model for predicting efficacy and survival in extensive-stage small-cell lung cancer patients undergoing immunotherapy: a single-center, retrospective cohort study

Xin Liu, M Z Li, Yalan Liu, Yudong Su, P. Chen, Yurong Li
article en

Abstract

Our study suggests that the serum ferritin change rate combined with the NLR and LDH inflammation model can serve as a biomarker for predicting the efficacy and survival outcomes of immunotherapy in ES-SCLC.

Frontiers in ImmunologyVol. 17
Tianjin Medical University Cancer Institute and Hospital (CN), The Central Hospital of Shaoyang (CN)
Tianjin Medical University, Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Good health and well-being
Openalex Percentile: Top 26%
Ferroptosis and cancer prognosis
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