Synchronous triple cancers of synchronous endometrial and ovarian carcinoma complicated by renal cancer: a case report

This case report adds to the limited literature on synchronous triple primary malignancies. For synchronous endometrial and ovarian cancer, distinguishing between primary tumors and metastases is clinically critical. Notably, the presence of MMRd subtype in such synchronous tumors does not inherently indicate Lynch syndrome. This case underscores the importance of integrating molecular testing and clinical manifestations to accurately diagnose multiple primary malignancies and formulate tailored treatment plans.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-03-11
DOI
https://doi.org/10.3389/fonc.2026.1668256
Primary Topic
Multiple and Secondary Primary Cancers
Type
article
Field-Weighted Citation Impact
0.00
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article

Synchronous triple cancers of synchronous endometrial and ovarian carcinoma complicated by renal cancer: a case report

Mu Xu, Jianhui Fu, Liangzhi Cai
Frontiers in Oncology
Multiple and Secondary Primary Cancers
article

Synchronous triple cancers of synchronous endometrial and ovarian carcinoma complicated by renal cancer: a case report

Mu Xu, Jianhui Fu, Liangzhi Cai
article en

Abstract

This case report adds to the limited literature on synchronous triple primary malignancies. For synchronous endometrial and ovarian cancer, distinguishing between primary tumors and metastases is clinically critical. Notably, the presence of MMRd subtype in such synchronous tumors does not inherently indicate Lynch syndrome. This case underscores the importance of integrating molecular testing and clinical manifestations to accurately diagnose multiple primary malignancies and formulate tailored treatment plans.

Frontiers in OncologyVol. 16
Fujian Medical University (CN), Fuzhou Maternity and Child Health Care Hospital (CN)
Good health and well-being
Openalex Percentile: Top 28%
Multiple and Secondary Primary Cancers
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