The efficacy and safety of platelet rich plasma and hyaluronic acid in the treatment of knee osteoarthritis: a meta-analysis

PRP has a good clinical therapeutic effect on KOA. Based on this meta-analysis, compared with simple intra-articular injection of HA, PRP can improve WOMAC score, VAS score, and IKDC index score after 6 months of treatment, and enhance patients' health status. In terms of the incidence of adverse events, the safety of the two treatment options is similar.

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Publication Details

Journal
Frontiers in Surgery
Published
2026-03-11
DOI
https://doi.org/10.3389/fsurg.2026.1725534
Primary Topic
Periodontal Regeneration and Treatments
Type
article
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article

The efficacy and safety of platelet rich plasma and hyaluronic acid in the treatment of knee osteoarthritis: a meta-analysis

Huiqiang Wu, Feimeng An, Haibin Zhang, Kai Yan et al.
Frontiers in Surgery
Periodontal Regeneration and Treatments
article

The efficacy and safety of platelet rich plasma and hyaluronic acid in the treatment of knee osteoarthritis: a meta-analysis

Huiqiang Wu, Feimeng An, Haibin Zhang, Kai Yan, Feng Wu, Jianzhong Wang, Genli Zhang, Junqian Wang
article en

Abstract

PRP has a good clinical therapeutic effect on KOA. Based on this meta-analysis, compared with simple intra-articular injection of HA, PRP can improve WOMAC score, VAS score, and IKDC index score after 6 months of treatment, and enhance patients' health status. In terms of the incidence of adverse events, the safety of the two treatment options is similar.

Frontiers in SurgeryVol. 13
Second Affiliated Hospital of Inner Mongolia Medical University (CN), Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine (CN)
Industry, innovation and infrastructure
Openalex Percentile: Top 25%
Periodontal Regeneration and Treatments
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