Prioritization of adverse events related to integrase inhibitors and NNRTIs: a disproportionality analysis using data from the FAERS database
This study provides a systematic framework for evaluating post-marketing AEs of INSTIs and NNRTIs using a semi-quantitative scoring system. Our findings identified five high-priority AEs that require clinical validation and further investigation.
Authors
- Yoshihiro Noguchi (ORCID: https://orcid.org/0000-0002-9110-9604)
- Mayur Sarangdhar (ORCID: https://orcid.org/0000-0001-9247-8375)
- Jifang Zhou (ORCID: https://orcid.org/0000-0003-2590-8667)
- Shuang Xia (ORCID: https://orcid.org/0000-0002-1059-1794)
- Gao-yang Wang
Institutions
- Cincinnati Children's Hospital Medical Center (US)
- Inserm (FR)
- China Pharmaceutical University (CN)
- Gifu Pharmaceutical University (JP)
- Sorbonne Université (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Pitié-Salpêtrière Hospital (FR)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2026-02-17
- DOI
- https://doi.org/10.1093/jac/dkag074
- Primary Topic
- Pharmacovigilance and Adverse Drug Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00