Synthesis of acyl hydrazide derivatives of α-naphthalene acetic acid as COX-2 inhibitors: <i>in vitro</i> evaluation, molecular docking and DFT studies
In general, the computational as well as experimental consequences specify that compound 13 is a potent COX-2 inhibitor.
Authors
- Muhammad Ayaz (ORCID: https://orcid.org/0000-0002-8539-1017)
- M. Sohail Ahmad
- Aftab Alam (ORCID: https://orcid.org/0000-0003-0475-2376)
- Tanzeela Ahmad Shah
- Syed Adnan Ali Shah
- Amrina Bibi
- Ghulam Fareed
- Aamir Qayum
- Mumtaz Ali
- Sumaira Naz
Institutions
- Pakistan Council of Scientific & Industrial Research (PK)
- Rawalpindi Medical University (PK)
- Rawalpindi Women University
- University of Malakand (PK)
- Universiti Teknologi MARA (MY)
Publication Details
- Journal
- Future Medicinal Chemistry
- Published
- 2026-03-11
- DOI
- https://doi.org/10.1080/17568919.2026.2642677
- Primary Topic
- Inflammatory mediators and NSAID effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00