Diabetic foot ulcer: a systematic review of risk factors
The development of DFUs may be associated with various factors, including: a history of previous DFUs; amputation or clinical atherosclerosis syndrome, such as peripheral arterial and cerebrovascular disease; the severity of diabetes; and various clinical signs regarding the patient's foot. The low certainty of evidence for most of these factors indicates that there is still a gap in knowledge regarding the early detection of foot ulcers in people with diabetes. A large prospective study could identify more precisely which factors are the most significant. Contemporary technology could use such data to create devices that would be able to predict DFUs so they can be prevented or treated earlier, which would reduce the possibility of lower limb amputation.
Authors
- Mihai Ionac (ORCID: https://orcid.org/0000-0002-9214-302X)
- Eftychios Protopapadakis (ORCID: https://orcid.org/0000-0003-3876-0024)
- Vaia Lampadiari
- George Geroulakos (ORCID: https://orcid.org/0000-0003-0310-2726)
- Michael A. Lazaris
- Georgios M. Pappas (ORCID: https://orcid.org/0000-0002-9687-0873)
- Adriane E. Napp (ORCID: https://orcid.org/0000-0003-0435-1281)
- Nikolaos Doulamis
- Anastasios Doulamis
- Günther Silbernagel
- Maria-Erofili S Lazari
- Panagiotis Halvatsiotis
- Katerina Angeli-Doulami
- Andreas M Lazaris
Institutions
- National Technical University of Athens (GR)
- University of Patras (GR)
- National and Kapodistrian University of Athens (GR)
- Medical University of Graz (AT)
- West University of Timişoara (RO)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Journal of Wound Care
- Published
- 2026-03-02
- DOI
- https://doi.org/10.12968/jowc.2023.0017
- Citations
- 1
- Primary Topic
- Diabetic Foot Ulcer Assessment and Management
- Type
- article
- Field-Weighted Citation Impact
- 30.73