The potential, perils and pitfalls of Artificial intelligence (AI) in Assisted Reproductive Technologies (ART)

The applications of Artificial intelligence (AI) have exponentially increased in all aspects of life, including within Assisted Reproductive Technologies (ART). Although there is tremendous promise demonstrated by AI assisted tools, there are concerning limitations and cautions to heed before widespread use is adopted into everyday clinical practice. The aim of this review is to offer healthcare providers and researchers an overview of AI applications and to assist them in independently reviewing and appraising AI research in its application to ART. We review different types of AI technologies while exploring current research of applications of AI within ART. Specific applications include embryo and gamete selection and AI as a clinical decision-making support system. We summarize the benefits of integrating AI into an ART setting and describe the known limitations and challenges of this technology in its application to our missions as clinicians, educators and scholars. We consider the ethical implications of AI within ART and equip clinicians and researchers with a framework to critically appraise, evaluate and review research utilizing AI specifically within the setting of ART. We present current international guidance and governance that can be adapted to publishing and reporting AI research in ART.

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Publication Details

Journal
Reproductive Biology and Endocrinology
Published
2026-03-11
DOI
https://doi.org/10.1186/s12958-026-01542-z
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.00
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article

The potential, perils and pitfalls of Artificial intelligence (AI) in Assisted Reproductive Technologies (ART)

David B. Seifer, Akanksha Garg
Reproductive Biology and Endocrinology
Artificial Intelligence in Healthcare and Education
article

The potential, perils and pitfalls of Artificial intelligence (AI) in Assisted Reproductive Technologies (ART)

David B. Seifer, Akanksha Garg
article en

Abstract

The applications of Artificial intelligence (AI) have exponentially increased in all aspects of life, including within Assisted Reproductive Technologies (ART). Although there is tremendous promise demonstrated by AI assisted tools, there are concerning limitations and cautions to heed before widespread use is adopted into everyday clinical practice. The aim of this review is to offer healthcare providers and researchers an overview of AI applications and to assist them in independently reviewing and appraising AI research in its application to ART. We review different types of AI technologies while exploring current research of applications of AI within ART. Specific applications include embryo and gamete selection and AI as a clinical decision-making support system. We summarize the benefits of integrating AI into an ART setting and describe the known limitations and challenges of this technology in its application to our missions as clinicians, educators and scholars. We consider the ethical implications of AI within ART and equip clinicians and researchers with a framework to critically appraise, evaluate and review research utilizing AI specifically within the setting of ART. We present current international guidance and governance that can be adapted to publishing and reporting AI research in ART.

Reproductive Biology and EndocrinologyVol. 24(1)
Yale University (US)
Gender equality
Openalex Percentile: Top 29%
Artificial Intelligence in Healthcare and Education
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