Equivalent efficacy of left versus right hemisphere accelerated intermittent theta burst stimulation for major depressive disorder
Accelerated iTBS to the right DLPFC appears to have equivalent efficacy as aiTBS to the left DLPFC in terms of magnitude of reduction of depressive, anxious, and anhedonic symptoms in a late-life population. However, connectivity changes associated with treatment were asymmetric, and may reflect hemispheric lateralization of functional network responses to iTBS. Further work is needed to confirm the comparative efficacy and network dynamics of left versus right hemisphere aiTBS for depression.
Authors
- Gregory Nikogosyan
- C. C. Abbott
- Andrei A. Vakhtin
- Crystal A. Garcia
- Tessa Olmstead
- Thomas R. Jones (ORCID: https://orcid.org/0000-0001-5824-5324)
- Benjamin C. Gibson (ORCID: https://orcid.org/0000-0003-3726-0917)
- Elizabeth Richardson (ORCID: https://orcid.org/0000-0003-0912-9575)
- Joel Upston
- Orrin Myers (ORCID: https://orcid.org/0000-0002-6291-2027)
- Alexander Win
- Justine Yang
- Brant W. Hager
- Ali Nakip
- Samuel MacDonald
- Danielle Farrar (ORCID: https://orcid.org/0000-0003-2040-6844)
- Samuel Reyes
- Cesar J. Ojeda
- Shawn Hazlewood
- Dorothy H. Bowers-Wu
- Robert DeBurlo
- Alyssa Velasco
- Pearl Huynh
- Adam Littleton
- Davin K. Quinn
- Julian David
- Justin R. Davis
- Jordan G. Lee
- Karen Luo
Institutions
- Mind Research Network (US)
- University of New Mexico (US)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2026-03-11
- DOI
- https://doi.org/10.3389/fpsyt.2026.1745388
- Primary Topic
- Transcranial Magnetic Stimulation Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00