Population pharmacokinetics of meropenem in critically ill adult patients receiving extracorporeal membrane oxygenation—an ASAP ECMO study

A meropenem dose of 1 g every 8 h as continuous infusion is safe and efficacious in most critically ill patients receiving ECMO with or without concomitant RRT.

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Publication Details

Journal
Journal of Antimicrobial Chemotherapy
Published
2026-02-24
DOI
https://doi.org/10.1093/jac/dkag090
Primary Topic
Antibiotics Pharmacokinetics and Efficacy
Type
article
Field-Weighted Citation Impact
0.00
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article

Population pharmacokinetics of meropenem in critically ill adult patients receiving extracorporeal membrane oxygenation—an ASAP ECMO study

Sam Rudham, Fay Burrows, Arne Diehl, Bianca Levkovich et al.
Journal of Antimicrobial Chemotherapy
Antibiotics Pharmacokinetics and Efficacy
article

Population pharmacokinetics of meropenem in critically ill adult patients receiving extracorporeal membrane oxygenation—an ASAP ECMO study

Sam Rudham, Fay Burrows, Arne Diehl, Bianca Levkovich, H. Kim, Young‐Jae Cho, Rachael L. Parke, Claire Reynolds, Shay McGuinness, Amanda Corley, Susan Welch, Jay Roberts, Jenny Ordoñez, Vesa Cheng, Sung Yoon Lim, Xin Liu, Vincent Pellegrino, Steven C Wallis, Eileen Gilder, John F Fraser, Mohd H Abdul–Aziz, Hergen Buscher, Kiran Shekar
article en

Abstract

A meropenem dose of 1 g every 8 h as continuous infusion is safe and efficacious in most critically ill patients receiving ECMO with or without concomitant RRT.

Journal of Antimicrobial ChemotherapyVol. 81(4)
Bond University (AU), Queensland Health (AU), University of Auckland (NZ), Queensland University of Technology (AU), The University of Queensland (AU), Université de Montpellier (FR), Royal Brisbane and Women's Hospital (AU), Auckland City Hospital (NZ), The Alfred Hospital (AU), Seoul National University Bundang Hospital (KR), UNSW Sydney (AU), St Vincent's Hospital Sydney (AU), Metro South Health (AU), St Vincent’s Private Hospital Sydney (AU), St Vincent's Clinic (AU), Prince Charles Hospital (AU), Monash University (AU), Université de Nîmes (FR)
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Openalex Percentile: Top 26%
Antibiotics Pharmacokinetics and Efficacy
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