Microbiological Characteristics and Clinical Outcomes of Periprosthetic Infections Following Oncologic Megaprosthetic Reconstruction: A Retrospective Cohort Study

Two-stage revision remains the most effective strategy for PJI management in megaprostheses. DAIR may control acute infection but is suboptimal for definitive treatment. Individualized, multidisciplinary approaches are essential to improve outcomes in this high-risk population.

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Publication Details

Journal
Pathogens
Published
2026-03-11
DOI
https://doi.org/10.3390/pathogens15030306
Primary Topic
Orthopedic Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Microbiological Characteristics and Clinical Outcomes of Periprosthetic Infections Following Oncologic Megaprosthetic Reconstruction: A Retrospective Cohort Study

Vasileios Petrakis, Ioannis G. Trikoupis, Alexandros Zikopoulos, Andreas G. Tsantes et al.
Pathogens
Orthopedic Infections and Treatments
article

Microbiological Characteristics and Clinical Outcomes of Periprosthetic Infections Following Oncologic Megaprosthetic Reconstruction: A Retrospective Cohort Study

Vasileios Petrakis, Ioannis G. Trikoupis, Alexandros Zikopoulos, Andreas G. Tsantes, Panayiotis Gavriil, Vasileios Karampikas, P. Ioannou, V. Kontogeorgakos, Panayiotis J. Papagelopoulos, Olga Savvidou, Stavros Goumenos, Dimitrios V. Papadopoulos, Anastasios G. Roustemis
article en

Abstract

Two-stage revision remains the most effective strategy for PJI management in megaprostheses. DAIR may control acute infection but is suboptimal for definitive treatment. Individualized, multidisciplinary approaches are essential to improve outcomes in this high-risk population.

PathogensVol. 15(3)
University of Crete (GR), Democritus University of Thrace (GR), National and Kapodistrian University of Athens (GR), Leeds Teaching Hospitals NHS Trust (GB), Laiko General Hospital of Athens (GR), St Savas Hospital (GR), Agia Olga Hospital (GR)
No poverty
Openalex Percentile: Top 27%
Orthopedic Infections and Treatments
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