Relative maternal protection against type 1 diabetes: a combined analysis of five observational studies

Our analyses suggest intrauterine exposure to maternal type 1 diabetes is associated with long-lasting relative protection against offspring type 1 diabetes, which is independent of genetic susceptibility as measured by T1D-GRS2.

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Publication Details

Journal
The Journal of Clinical Endocrinology & Metabolism
Published
2026-03-08
DOI
https://doi.org/10.1210/clinem/dgag103
Primary Topic
Gestational Diabetes Research and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Relative maternal protection against type 1 diabetes: a combined analysis of five observational studies

A. G. HILL, Colin Dayan, Georgina Mortimer, Emma Hedlund et al.
The Journal of Clinical Endocrinology & Metabolism
Gestational Diabetes Research and Management
article

Relative maternal protection against type 1 diabetes: a combined analysis of five observational studies

A. G. HILL, Colin Dayan, Georgina Mortimer, Emma Hedlund, Angus G. Jones, C. Williams, Diane P. Fraser, Annelie Carlsson, Lowri Allen, Peter N. Taylor, Kathleen M Gillespie, William A Hagopian, Johnny Ludvigsson, Richard A Oram, Stephen S Rich, Maria J Redondo, Suna Onengut-Gumuscu
article en

Abstract

Our analyses suggest intrauterine exposure to maternal type 1 diabetes is associated with long-lasting relative protection against offspring type 1 diabetes, which is independent of genetic susceptibility as measured by T1D-GRS2.

The Journal of Clinical Endocrinology & Metabolism
Linköping University (SE), Baylor College of Medicine (US), Kristianstad University (SE), University of Exeter (GB), Royal Devon & Exeter NHS Foundation Trust (GB), University Hospital of Wales (GB), University of Bristol (GB), University Dental Hospital on Cardiff University (GB), NIHR Exeter Clinical Research Facility (GB), Skåne University Hospital (SE), Texas Children's Hospital (US), Centralsjukhuset Kristianstad (SE), Linköping University Hospital (SE), University of Virginia (US), Indiana University (US)
Zero hunger
Openalex Percentile: Top 26%
Gestational Diabetes Research and Management
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Relative maternal protection against type 1 diabetes: a combined analysis of five observational studies — A. G. HILL, Colin Dayan, et al. · The Journal of Clinical Endocrinology & Metabolism (2026) | TGRS Research Map | TGRS