Delayed-Onset Cariprazine-Induced Akathisia: A Case Report

This case highlights the challenge of distinguishing akathisia from primary anxiety disorders, in addition to considering this diagnosis beyond the initial treatment period. Akathisia symptoms most commonly present within 4 weeks of initiation or titration of antidopaminergic treatment. However, this timeline may be delayed with cariprazine due to its pharmacokinetic and pharmacodynamic properties.

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Publication Details

Journal
Clinical Neuropharmacology
Published
2026-03-02
DOI
https://doi.org/10.1097/wnf.0000000000000676
Primary Topic
Hallucinations in medical conditions
Type
article
Field-Weighted Citation Impact
0.00
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article

Delayed-Onset Cariprazine-Induced Akathisia: A Case Report

Zachary Goodrich, Drew Grehan
Clinical Neuropharmacology
Hallucinations in medical conditions
article

Delayed-Onset Cariprazine-Induced Akathisia: A Case Report

Zachary Goodrich, Drew Grehan
article en

Abstract

This case highlights the challenge of distinguishing akathisia from primary anxiety disorders, in addition to considering this diagnosis beyond the initial treatment period. Akathisia symptoms most commonly present within 4 weeks of initiation or titration of antidopaminergic treatment. However, this timeline may be delayed with cariprazine due to its pharmacokinetic and pharmacodynamic properties.

Clinical Neuropharmacology
Eastern Virginia Medical School (US), Old Dominion University (US)
Good health and well-being
Openalex Percentile: Top 32%
Hallucinations in medical conditions
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