Diagnostic Yield of Tongue Swab- Compared to Sputum-Based Molecular Testing for Tuberculosis in Four High-Burden Countries
Tongue swab-based molecular testing with MiniDock MTB achieved non-inferior diagnostic yield compared with sputum-based molecular testing. These findings support scale-up of swab-based platforms as a cost-efficient alternative, particularly where sputum collection is challenging or smear microscopy remains the primary diagnostic method.
Authors
- Caitlin A. Moe (ORCID: https://orcid.org/0000-0002-9318-2514)
- Monde Muyoyeta (ORCID: https://orcid.org/0000-0003-3609-5403)
- Alfred Andama (ORCID: https://orcid.org/0000-0003-0526-0007)
- Hien Nam Le (ORCID: https://orcid.org/0000-0003-3131-4080)
- Ha Phan (ORCID: https://orcid.org/0000-0003-3073-2811)
- Rebecca Crowder (ORCID: https://orcid.org/0000-0001-6374-3088)
- Charles Yu
- Rita Kabuleta Luswata
- Jheannie Barrameda
- A. Cattamanchi
- Seke Muzazu
- Claudia M Denkinger
Institutions
- Centre for Infectious Disease Research in Zambia (ZM)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Center for Promotion of Advancement of Society (VN)
- Novosibirsk Tuberculosis Research Institute (RU)
- University of California, Irvine Medical Center (US)
- Vietnam National University of Agriculture (VN)
- German Center for Infection Research (DE)
- World Health Organization - Uganda (UG)
- Global Brain Health Institute (US)
- Makerere University (UG)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2026-02-09
- DOI
- https://doi.org/10.1093/cid/ciag077
- Citations
- 1
- Primary Topic
- Traditional Chinese Medicine Studies
- Type
- article
- Field-Weighted Citation Impact
- 51.14