Leptospirosis Incidence at Four Sites in Sub-Saharan Africa and South East Asia: An International Multi-Site Hybrid Surveillance Study
Leptospirosis incidence was high at the Laos, Malawi, and Mozambique sites and at the upper end of published incidence estimates from the Asia and Africa regions. We recommend more leptospirosis incidence studies be done in areas lacking data to strengthen leptospirosis global burden of disease estimates and to stimulate progress on diagnosis, management, and control.
Authors
- Nicholas Feasey (ORCID: https://orcid.org/0000-0003-4041-1405)
- Yoel Lubell (ORCID: https://orcid.org/0000-0002-0237-1070)
- Risara Jaksuwan (ORCID: https://orcid.org/0000-0002-4258-9058)
- Alessandro Gerada
- Shunmay Yeung (ORCID: https://orcid.org/0000-0002-0997-0850)
- Kevin C. Kain (ORCID: https://orcid.org/0000-0001-6068-1272)
- Becca L. Handley (ORCID: https://orcid.org/0000-0003-2208-8229)
- M Picardeau
- Florian P. Maurer (ORCID: https://orcid.org/0000-0001-8353-5964)
- Marie Voice
- Eleanor MacPherson (ORCID: https://orcid.org/0000-0002-7142-1158)
- Vilayouth Phimolsarnnousith (ORCID: https://orcid.org/0000-0001-8180-0007)
- Suzanne Keddie (ORCID: https://orcid.org/0000-0003-1254-7794)
- Mabvuto Chimenya
- Catherine M. Davis (ORCID: https://orcid.org/0000-0001-9654-3509)
- Elizabeth Fitchett (ORCID: https://orcid.org/0000-0002-6767-6094)
- Manivanh Vongsouvath (ORCID: https://orcid.org/0000-0002-2249-7367)
- Amphone Sengduangphachanh
- Heidi Hopkins (ORCID: https://orcid.org/0000-0003-1076-6758)
- Joseph Chipanga (ORCID: https://orcid.org/0000-0002-3938-4983)
- Justin Dixon (ORCID: https://orcid.org/0000-0002-7706-7305)
- Colin G. Fink (ORCID: https://orcid.org/0000-0002-8008-5870)
- Polycarp Mogeni (ORCID: https://orcid.org/0000-0003-1926-7576)
- Ioana D. Olaru (ORCID: https://orcid.org/0000-0003-3392-9257)
- Ampai Tanganuchitcharnchai (ORCID: https://orcid.org/0000-0001-5439-5376)
- Núria Balanza (ORCID: https://orcid.org/0000-0002-3581-0383)
- Molly Sibanda
- Oliver Baerenbold
- Justina Bramugy (ORCID: https://orcid.org/0000-0002-2350-5584)
- Michael A. Miles (ORCID: https://orcid.org/0000-0002-5834-8734)
- Sara Ajanovic (ORCID: https://orcid.org/0000-0002-6137-8619)
- Anélsio Cossa (ORCID: https://orcid.org/0000-0002-3616-8935)
- Christian Bottomley (ORCID: https://orcid.org/0000-0002-5241-8412)
- Tsitsi Bandason (ORCID: https://orcid.org/0000-0003-0066-8345)
- Forget Makoga
- David G. Lalloo (ORCID: https://orcid.org/0000-0001-7680-2200)
- John Stenos (ORCID: https://orcid.org/0000-0001-5465-2926)
- Chrissy h. Roberts (ORCID: https://orcid.org/0000-0003-1064-5980)
- Rashida A. Ferrand (ORCID: https://orcid.org/0000-0002-7660-9176)
- Siho Sengsavang
- Quique Bassat (ORCID: https://orcid.org/0000-0003-0875-7596)
- Manophab Luangraj (ORCID: https://orcid.org/0000-0002-8801-5738)
- Ethel Dauya (ORCID: https://orcid.org/0000-0003-3241-2512)
- Jayne Jones
- Campos Mucasse
- Khamfong Kunlaya
- Edward Green (ORCID: https://orcid.org/0000-0002-2440-4355)
- Marta Valente
- Chelsea Nguyen (ORCID: https://orcid.org/0000-0003-0674-7423)
- Michelle Durkin
- Tapan K. Bhattacharyya
- Brad Amos
- Zumilda Boca
- Jessica Jervis
- Stéphanie Baghoumina
- Somyoth Douangphachanh
- Khamxeng Khounpaseuth
- Sengchanh Manichan
- Hira Tanvir
- Msopole Wamaka
- Clare I R Chandler
- John Bradley
- John A. Crump
- David C. W. Mabey
- Stuart Blacksell
- Sham Lal
- Mayfong Mayxay
- Xavier de Lamballerie
- Pankaj Lal
- Stephen R Graves
- Somvai Singha
- Paul N Newton
- Elizabeth A Ashley
- Coll D Hutchison
- James E Ussher
- Katharina Kranzer
- Audrey Dubot-Pérès
Institutions
- University of London (GB)
- University of Liverpool (GB)
- Institut Pasteur (FR)
- Liverpool School of Tropical Medicine (GB)
- Mahosot Hospital (LA)
- Malawi-Liverpool-Wellcome Trust Clinical Research Programme (MW)
- Angkor Hospital for Children (KH)
- University of Oxford (GB)
- London School of Hygiene & Tropical Medicine (GB)
- Biomedical Research and Training Institute (ZW)
- Manhiça Health Research Centre (MZ)
- Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LA)
- Barcelona Institute for Global Health (ES)
- Universitat de Barcelona (ES)
- University of Otago (NZ)
- Wellcome Trust (GB)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2026-01-12
- DOI
- https://doi.org/10.1093/ofid/ofag021
- Primary Topic
- Leptospirosis research and findings
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- OPEC Fund for International Development
- University of Otago
- Wellcome Trust
- Micropathology
- Government of the United Kingdom
- University of Warwick
- University of Oxford
- University of Glasgow
- Institut National de la Santé et de la Recherche Médicale
- University of Toronto
- Institució Catalana de Recerca i Estudis Avançats
- Mahidol University
- Universitat de Barcelona