Dose-stratified analysis of acitretin vs. bexarotene in mycosis fungoides: a retrospective cohort study
In this retrospective cohort of 81 patients with mycosis fungoides treated with oral acitretin, overall response rate was 61% (9% complete, 52% partial) and median time to next treatment was around 23–24 months in moderate-/high-dose groups. Adverse events were infrequent and no cases of hypothyroidism were observed. These findings support acitretin as a well-tolerated, accessible systemic retinoid option for patients with mycosis fungoides.
Authors
- Beth A. Childs (ORCID: https://orcid.org/0000-0003-3406-8890)
- Todd A. Aguilera (ORCID: https://orcid.org/0000-0002-3734-3758)
- Kiran A. Kumar (ORCID: https://orcid.org/0000-0003-4278-1872)
- Heather W Goff
- Victoria Garfinkel
- Brielle E Johnson
Institutions
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- British Journal of Dermatology
- Published
- 2026-03-07
- DOI
- https://doi.org/10.1093/bjd/ljag073
- Primary Topic
- Retinoids in leukemia and cellular processes
- Type
- article
- Field-Weighted Citation Impact
- 0.00