Suspension Adaptation of Immortalized Lamb Testis (iLT) Cells in Serum-Reduced Media and Evaluation of Goatpox Virus (GTPV-AV41) Replication
This study presents a scalable suspension-culture platform by adapting iLT cells under serum-reduced conditions, enabling stable high-density growth and efficient replication of goatpox virus for cost-effective vaccine manufacturing.
Authors
- Caixia Wang
- Xiangmei Lin
- Zhen Yang (ORCID: https://orcid.org/0000-0001-6057-6958)
- Chunyan Feng
- Fanqi Sun
- Haoyang Yu
- Shaoqiang Wu
- Ting Zhang
Institutions
- Nanjing Agricultural University (CN)
- Chinese Academy of Inspection and Quarantine (CN)
Publication Details
- Journal
- Journal of AOAC International
- Published
- 2026-03-03
- DOI
- https://doi.org/10.1093/jaoacint/qsag019
- Primary Topic
- Poxvirus research and outbreaks
- Type
- article
- Field-Weighted Citation Impact
- 0.00