Prognostic value of the triglyceride–glucose index for ICU mortality in non-diabetic sepsis: a restricted cubic spline analysis

The TyG index is independently associated with ICU mortality in non-diabetic sepsis and exhibits a clear U-shaped pattern. The external validation cohort demonstrated a similar risk trend, supporting the broader applicability of TyG as a simple metabolic marker for risk stratification.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-03-09
DOI
https://doi.org/10.3389/fendo.2026.1752068
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Prognostic value of the triglyceride–glucose index for ICU mortality in non-diabetic sepsis: a restricted cubic spline analysis

Qianfei Liu, Peijun Liu, Yaomei Luo, Lijun Gong et al.
Frontiers in Endocrinology
Sepsis Diagnosis and Treatment
article

Prognostic value of the triglyceride–glucose index for ICU mortality in non-diabetic sepsis: a restricted cubic spline analysis

Qianfei Liu, Peijun Liu, Yaomei Luo, Lijun Gong, Dan Gui, Yanli Cao, Ming Min
article en

Abstract

The TyG index is independently associated with ICU mortality in non-diabetic sepsis and exhibits a clear U-shaped pattern. The external validation cohort demonstrated a similar risk trend, supporting the broader applicability of TyG as a simple metabolic marker for risk stratification.

Frontiers in EndocrinologyVol. 17
The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture (CN)
Natural Science Foundation of Hubei Province
Good health and well-being
Openalex Percentile: Top 30%
Sepsis Diagnosis and Treatment
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