Identification of plasma biomarkers in a PTZ-induced Sudden Unexpected Death-like model through integrated proteomics and metabolomics methods
These findings nominate candidate circulating signatures associated with seizure-related sudden death in this SUDEP-like paradigm. Translation to SUDEP risk stratification or forensic application requires independent validation in well-phenotyped human cohorts using standardized SUDEP classification.
Authors
- Gaolin Zheng
- Yinyu Chen
- Qianyun Nie
- Xinyan Yang
- Peng Zhang
Institutions
- Academy of Medical Sciences (GB)
- Hainan Medical University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-03-09
- DOI
- https://doi.org/10.3389/fmed.2026.1774546
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hainan Province
- Hainan Medical University
- Education Department of Hainan Province