A dynamic nomogram for predicting axillary pathological complete response and its prognostic value in HER2-positive breast cancer

Our study developed and validated a preoperative nomogram that predicts apCR in HER2-positive BC by integrating three readily available clinical variables. This model demonstrates the potential to preoperatively identify candidates who may be suitable for axillary de-escalation strategies, pending future multi-center prospective validation. The established prognostic value of apCR in our cohort underscores its relevance as a critical clinical endpoint.