Models Integrating Disease Heterogeneity and <scp>MPA</scp> Exposure Predict Systemic and Renal Efficacy of Mycophenolate in Pediatric Lupus Nephritis
We present predictive models that incorporate a comprehensive profile of disease and drug-related heterogeneity to stratify pediatric patients with LN by their likelihood of responding to MMF. This integrated approach offers a strategy to optimize initial treatment selection by directly addressing the challenge of clinical variability.
Authors
- Z. Huang (ORCID: https://orcid.org/0000-0002-7195-3189)
- Baojing Liu
- Xing Liu (ORCID: https://orcid.org/0000-0002-7480-5085)
- Xi Jiang (ORCID: https://orcid.org/0000-0003-1932-442X)
- Kejing Tang (ORCID: https://orcid.org/0000-0002-5454-4666)
- Xiaoman Liu (ORCID: https://orcid.org/0000-0001-9879-9540)
- Jingxuan Lin
- Lizhi Chen
- Pan Chen
- Min Huang
Institutions
- Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy
- Published
- 2026-03-09
- DOI
- https://doi.org/10.1002/phar.70127
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00