A case of autosomal dominant polycystic kidney disease with multiple bilateral spontaneous retroperitoneal hemorrhages

We experienced a 45-year-old male with ADPKD who developed spontaneous retroperitoneal hemorrhages with hypertension in the right subcapsular renal space without trauma. After his condition worsened with conservative management, he was treated by renal transarterial embolization (TAE). Over the next eight years, he experienced bilateral bleeding at three different sites and underwent repeated endovascular treatment with renal TAE to stop the bleeding. After the fourth occurrence, the patient underwent hemodialysis. Although renal cysts and urinary tract bleeding occur frequently in ADPKD, retroperitoneal hemorrhage is rare; however, TAE is both effective and a good way to preserve renal function.

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Publication Details

Journal
CEN Case Reports
Published
2026-03-09
DOI
https://doi.org/10.1007/s13730-025-01079-x
Primary Topic
Genetic and Kidney Cyst Diseases
Type
article
Field-Weighted Citation Impact
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article

A case of autosomal dominant polycystic kidney disease with multiple bilateral spontaneous retroperitoneal hemorrhages

Masato Mizuta, Yoshifumi Ubara, Hiroki Mizuno, Motoaki Miyazono et al.
CEN Case Reports
Genetic and Kidney Cyst Diseases
article

A case of autosomal dominant polycystic kidney disease with multiple bilateral spontaneous retroperitoneal hemorrhages

Masato Mizuta, Yoshifumi Ubara, Hiroki Mizuno, Motoaki Miyazono, Yuki Oba, Takehiko Wada, Akinari Sekine, Makoto Fukuda, Eiko Hasegawa, Tatsuya Suwabe, Naoki Sawa, Masayuki Yamanouchi
article en

Abstract

We experienced a 45-year-old male with ADPKD who developed spontaneous retroperitoneal hemorrhages with hypertension in the right subcapsular renal space without trauma. After his condition worsened with conservative management, he was treated by renal transarterial embolization (TAE). Over the next eight years, he experienced bilateral bleeding at three different sites and underwent repeated endovascular treatment with renal TAE to stop the bleeding. After the fourth occurrence, the patient underwent hemodialysis. Although renal cysts and urinary tract bleeding occur frequently in ADPKD, retroperitoneal hemorrhage is rare; however, TAE is both effective and a good way to preserve renal function.

CEN Case ReportsVol. 15(2)
Saga University (JP), Toranomon Hospital (JP)
Good health and well-being
Openalex Percentile: Top 28%
Genetic and Kidney Cyst Diseases
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A case of autosomal dominant polycystic kidney disease with multiple bilateral spontaneous retroperitoneal hemorrhages — Masato Mizuta, Yoshifumi Ubara, et al. · CEN Case Reports (2026) | TGRS Research Map | TGRS