Leukotriene receptor antagonists and eosinophilic granulomatosis with polyangiitis: a disproportionality analysis from FAERS, JADER, CVAR databases integrated with network pharmacology
Our study revealed LTRAs could increase the risk of EGPA, and initially explored potential genes and mechanisms of LTRAs-induced EGPA. It is helpful for clinicians to be alerted to the risk of EGPA during LTRAs administration.
Authors
- Cuilv Liang (ORCID: https://orcid.org/0000-0003-4400-3038)
- Pingping Zhuo
- yin zhang
Institutions
- Fujian Medical University (CN)
- Fuzhou Pulmonary Hospital of Fujian (CN)
- Second Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-03-09
- DOI
- https://doi.org/10.1371/journal.pone.0343084
- Primary Topic
- Pharmacovigilance and Adverse Drug Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00