Maternal Acetaminophen Use and Child Neurodevelopment
The findings of this cohort study in Taiwan suggest that positive associations were observed between maternal prenatal acetaminophen prescriptions and offspring's ADHD or ASDs in the full cohort but not in the sibling-matched analyses. A substantial divergence in associations in the sibling bidirectional analyses indicates unaddressed sources of bias and prevents firm conclusions from being drawn using the sibling design.
Authors
- Pei‐Chen Lee (ORCID: https://orcid.org/0000-0001-7813-0823)
- Zeyan Liew (ORCID: https://orcid.org/0000-0002-9424-7869)
- Julia E. Heck (ORCID: https://orcid.org/0000-0001-8713-8413)
- Onyebuchi A. Arah (ORCID: https://orcid.org/0000-0002-9067-1697)
- Giselle Bellia
- Yu-Hsuan Chuang
- Ying-Yeh Chen
- Ya-Hui Hu
- Haoran Zhuo
- Chia-Ni Lin
- Chung-Yi Li
Institutions
- University of North Texas (US)
- Los Angeles County Department of Public Health (US)
- National Yang Ming Chiao Tung University (TW)
- University of California, Los Angeles (US)
- Taipei City Hospital (TW)
- Providence Center (US)
- National Cheng Kung University (TW)
Publication Details
- Journal
- JAMA Pediatrics
- Published
- 2026-03-09
- DOI
- https://doi.org/10.1001/jamapediatrics.2026.0071
- Primary Topic
- Pregnancy and Medication Impact
- Type
- article
- Field-Weighted Citation Impact
- 0.00